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BD Dryslide
Nitrocefin
BBL DrySlide Nitrocefin is used for detecting â-lactamase production by bacteria. The chromogenic cephalosporin beta-lactamase test is a qualitative procedure for detecting the production of beta-lactamase by bacteria. The reaction is based on the production of a colored compound when the substrate, nitrocefin, is exposed to a ß-lactamase-producing culture. The enzyme, beta-lactamase, originally described by Abraham and Chain, is produced by various organisms and is a mechanism of their resistance to penicillins and cephalosporins. Test methods used to detect ß-lactamase include iodometric, acidimetric and chromogenic cephalosporin procedures. Some staphylococci may require induction (exposure to a ß-lactam agent) to increase production of beta-lactamase to detectable levels. According to standard references, any negative ß-lactamase test result from a non-induced stapylococcal isolate, despite the test method, should be confirmed by induction of the isolate and repeat testing. BBL DrySlide Nitrocefin employs nitrocefin, a cephalosporin compound first described by Glaxo Research (Middlesex, England), in the chromogenic cephalosporin test methodology. BD Dyslide Indole, Dyslide, indole, dryslide indole, BBL, BD, BBL Distributor, BBL Dealer, Order BBL, BD Distributor, BD Dealer, Order BD, Difco |
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